Exercise Modulates Brain Glucose Utilization Response to Acute Cocaine.

ABSTRACT: Exercise, a proven method of boosting health and wellness, is thought to act as a protective factor against many neurological and psychological diseases. Recent studies on exercise and drug exposure have pinpointed some of the neurological mechanisms that may characterize this protective factor. Using positron emission tomography (PET) imaging techniques and the glucose analog [¹⁸F]-Fluorodeoxyglucose (¹⁸F-FDG), our team sought to identify how chronic aerobic exercise modulates brain glucose metabolism (BGluM) after drug-naïve rats were exposed to an acute dose of cocaine. Using sedentary rats as a control group, we observed significant differences in regional BGluM. Chronic treadmill exercise treatment coupled with acute cocaine exposure induced responses in BGluM ac

SUBMITTER: Hanna C 

PROVIDER: S-EPMC9788493 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature