Extent of vascular plaque predicts future cardiovascular events in patients with systemic lupus erythematosus.

ABSTRACT:

Objective

Patients with SLE have increased prevalence of clinical cardiovascular disease (CVD) and subclinical atherosclerosis. Although 30-40% of patients with SLE have vascular plaque on ultrasound scanning, this study is the first to consider the relationship between total burden of plaque and subsequent CVD risk.

Methods

One hundred patients with SLE and without any previous clinical CVD underwent vascular ultrasound scans of both carotid and both common femoral bifurcations between 2011 and 2013. Clinical, serological, demographic and treatment data were collected at baseline. Patients were followed till 2020 to identify those who developed new onset coronary disease or stroke. Statistical analysis to identify factors associated with increased risk of developing CVD eve

SUBMITTER: Bakshi J 

PROVIDER: S-EPMC9788823 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature