Fibromyalgia, mood disorders, cognitive test results, cognitive symptoms and quality of life in systemic lupus erythematosus.

ABSTRACT:

Objectives

Cognitive dysfunction, and comorbidities such as mood disorder and fibromyalgia, are common in SLE. This study aims to explore the associations between fibromyalgia, mood disorders, cognitive symptoms and cognitive dysfunction in SLE patients, and their impact on quality of life.

Methods

We tested cognition in SLE patients and healthy controls, and evaluated cognitive symptoms, mood disorder, fibromyalgia, fatigue and quality of life using patient-reported outcome measures. We examined associations of these comorbidities with both patient-reported cognitive symptoms and cognitive test performance.

Results

High fibromyalgia symptom score and history of depression or anxiety were associated with cognitive dysfunction. There were no significant associations be

SUBMITTER: Raghunath S 

PROVIDER: S-EPMC9788827 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature