A Case of Lithium Encephalopathy with Therapeutic Lithium Levels: The Diagnostic Role of EEG.

ABSTRACT: Introduction. Lithium is considered a first-line therapy for both the acute phase and the maintenance of bipolar disorder. Many studies highlighted its neuroprotective and neuroplastic capacity suggesting a potential usefulness in the treatment of neurodegenerative diseases. Despite the undeniable efficacy, lithium clearly presents several adverse effects including neurotoxicity, also known as lithium encephalopathy, regarding both neurological, psychiatric, and cognitive side effects. In this case, adverse reactions are not always related to its serum levels, possibly appearing within the therapeutic range. Case Presentation. We analyzed the case of a bipolar patient who has been uncontinuosly treated with lithium salts since the onset of the psychopathological picture. Over

SUBMITTER: Carmassi C 

PROVIDER: S-EPMC9788879 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature