Time-scale analysis of the long-term variability of human gut microbiota characteristics in Chinese individuals.

ABSTRACT: Studying the dynamics and stability of the human gut microbiota over time is important for exploring their relationship with human health and developing treatment strategies for putative microbiome-related ailments. Here, we collected stool samples from seven healthy Chinese subjects at 1-month intervals between 2016 and 2020. Sequencing and bioinformatics analyses revealed that the bacteria in the collected fecal samples fluctuated over time, and the extent of these changes increased over time. Further, the average shared proportion value obtained using Sourcetracker2 was 63.5% for samples collected from the same individual in the preceding month, and over a 3-year period, this value decreased to 40.7%. Furthermore, the proportion of different bacteria in the gut microbiota of the differe

SUBMITTER: Han N 

PROVIDER: S-EPMC9789056 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature