Health state utility values for metastatic pancreatic cancer using a composite time trade-off based on the vignette-based approach in Japan.

ABSTRACT:

Backgrounds

Limited information is available on the utility values of metastatic pancreatic cancer, focusing on different health statuses, selected chemotherapy, and related grades 1/2 and 3/4 adverse events (AEs). We evaluated Japanese societal-based health-related utility values for metastatic pancreatic cancer by considering different grade toxicities commonly associated with chemotherapy using the vignette-based method.

Methods

We developed health status scenarios for patients with metastatic pancreatic cancer undergoing chemotherapy and conducted utility research using the developed scenarios in four steps: 'literature review,' 'exploratory interview,' 'content validation', and 'utility research'. In the development process, to consider the impact of AEs of chemotherapy

SUBMITTER: Takumoto Y 

PROVIDER: S-EPMC9789314 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature