Serum sodium level is inversely associated with new-onset diabetes in hypertensive patients.

ABSTRACT:

Background

Serum sodium level is associated with cardiovascular and endocrine health. Though decreased serum sodium is considered to be associated with reduced hypertension risk, some studies also found that it may increase the risk of diabetes. This study aimed to investigate the association of serum sodium with new-onset diabetes in hypertensive patients.

Methods

Based on the annual health examinations from 2011 to 2016 in Dongguan City, Guangdong, China, hypertensive patients without diabetes at baseline were selected. Logistic regression and restricted cubic spline were used to evaluate the association between serum sodium level and new-onset diabetes. Subgroup analysis was also conducted.

Results

A total of 4438 hypertensive patients with a mean age of 58.65 year

SUBMITTER: Cheng Q 

PROVIDER: S-EPMC9789394 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature