Carotenoid biosynthesis is associated with low-temperature adaptation in Rhodosporidium kratochvilovae.

ABSTRACT:

Background

Low temperatures greatly limit the growth of microorganisms. Low-temperature adaptation in microorganisms involves multiple mechanisms. Carotenoids are naturally occurring lipid-soluble pigments that act as antioxidants and protect cells and tissues from the harmful effects of free radicals and singlet oxygen. However, studies on the regulation of carotenoid biosynthesis at low temperatures in microorganisms are limited. In this study, we investigated the correlation between carotenoids and low-temperature adaptation in the cold-adapted strain of Rhodosporidium kratochvilovae YM25235.

Results

Carotenoid biosynthesis in YM25235 was inhibited by knocking out the bifunctional lycopene cyclase/phytoene synthase gene (RKCrtYB) using the established CRISPR/Cas9 gene-edi

SUBMITTER: Guo R 

PROVIDER: S-EPMC9789556 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature