Disconnectomics to unravel the network underlying deficits of spatial exploration and attention.

ABSTRACT: Spatial attention and exploration are related to a predominantly right hemispheric network structure. However, the areas of the brain involved and their exact role is still debated. Spatial neglect following right hemispheric stroke lesions has been frequently viewed as a model to study these processes in humans. Previous investigations on the anatomical basis on spatial neglect predominantly focused on focal brain damage and lesion-behaviour mapping analyses. This approach might not be suited to detect remote areas structurally spared but which might contribute to the behavioural deficit. In the present study of a sample of 203 right hemispheric stroke patients, we combined connectome lesion-symptom mapping with multivariate support vector regression to unravel the complex and disconnecte

SUBMITTER: Wiesen D 

PROVIDER: S-EPMC9789971 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature