Emerging frontiers in immuno- and gene therapy for cancer.

ABSTRACT:

Background aims

The field of cell and gene therapy in oncology has moved rapidly since 2017 when the first cell and gene therapies, Kymriah followed by Yescarta, were approved by the Food and Drug Administration in the United States, followed by multiple other countries. Since those approvals, several new products have gone on to receive approval for additional indications. Meanwhile, efforts have been made to target different cancers, improve the logistics of delivery and reduce the cost associated with novel cell and gene therapies. Here, we highlight various cell and gene therapy-related technologies and advances that provide insight into how these new technologies will speed the translation of these therapies into the clinic.

Conclusions

In this review, we provide a broa

SUBMITTER: Gustafson MP 

PROVIDER: S-EPMC9790040 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature