Risk of cardiovascular disease and loss in life expectancy in NAFLD.

ABSTRACT:

Background and aims

Conflicting evidence exists on cardiovascular disease (CVD) risk in patients with NAFLD, and data are lacking on whether NAFLD increases mortality after a CVD event. Moreover, life expectancy in NAFLD has not been studied. We therefore examined CVD risk and life expectancy in patients with NAFLD compared with the general population.

Approach and results

In this nationwide population-based cohort, all patients with NAFLD diagnosis and without baseline CVD (ascertaining from the Swedish National Patient Register from 1987 to 2016, n = 10,023) were matched 10:1 on age, sex, and municipality to individuals from the general population (controls, n = 96,313). CVD diagnosis and mortality were derived from national registers. Multistate models and flexible parame

SUBMITTER: Shang Y 

PROVIDER: S-EPMC9790251 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature