Anti-Mullerian hormone concentration is associated with central adiposity and reproductive hormones in expectant fathers.

ABSTRACT:

Objective

The role of the anti-Müllerian hormone (AMH) as an indicator of physical and reproductive health in men is unclear. We assessed the relationships between AMH and follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and metabolic parameters, in a cohort of expectant fathers.

Design

ORIGINS Project prospective cohort study.

Setting

Community-dwelling men.

Participants

Partners of pregnant women attending antenatal appointments.

Main outcome measures

Serum AMH, FSH, LH, testosterone, and metabolic parameters.

Results

In 485 expectant fathers, median age 33 years, median AMH was 40 pmol/L (quartiles 29, 56). AMH was inversely correlated with FSH, age, and body mass index (BMI) (correlation coefficients: -.32, -.24, and

SUBMITTER: Hadlow NC 

PROVIDER: S-EPMC9790283 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature