Understanding mammographic breast density profile in China: A Sino-Australian comparative study of breast density using real-world data from cancer screening programs.

ABSTRACT:

Aim

This study aims at understanding mammographic density profile in China by comparing the density between women in China and Australia.

Methods

Data of 3250 women aged 45-69 were obtained from the Cancer Screening Program in Urban China and data of 1384 Australian counterparts at same age range were gathered from the Lifepool project. Demographic and reproductive details and mammograms for each cohort were collected. Mammographic density was assessed using AutoDensity, and two metrics, percentage density (PD) and dense area (DA), were applied. T-tests were used to compare the means of mammographic density between two populations of all, premenopausal, and postmenopausal women. Two-way ANOVA was conducted to examine interactions of population (Chinese/Australian) and each v

SUBMITTER: Li T 

PROVIDER: S-EPMC9790382 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature