Mitochondrial Disease and Hearing Loss in Children: A Systematic Review.

ABSTRACT:

Objectives

Hearing loss is a clinical symptom, frequently mentioned in the context of mitochondrial disease. With no cure available for mitochondrial disease, supportive treatment of clinical symptoms like hearing loss is of the utmost importance. The aim of this study was to summarize current knowledge on hearing loss in genetically proven mitochondrial disease in children and deduce possible and necessary consequences in patient care.

Methods

Systematic literature review, including Medline, Embase, and Cochrane library. Review protocol was established and registered prior to conduction (International prospective register of systematic reviews-PROSPERO: CRD42020165356). Conduction of this review was done in accordance with MOOSE criteria.

Results

A total of 23 articl

SUBMITTER: Roesch S 

PROVIDER: S-EPMC9790539 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature