Non-metastatic muscle-invasive bladder cancer: the role of age in receiving treatment with curative intent.

ABSTRACT:

Objectives

To evaluate which patient and tumour characteristics are associated with remaining untreated in patients with potentially curable, non-metastatic muscle-invasive bladder cancer (MIBC), and to compare survival of untreated vs treated patients with similar characteristics.

Patients and methods

For this cohort study, 15 047 patients diagnosed with cT2-T4aN0/xM0/x urothelial MIBC between 2005 and 2019 were identified in the Netherlands Cancer Registry. Factors associated with remaining untreated were identified using logistic regression analyses. Interhospital variation was assessed using multilevel analysis. Using a propensity score, the median overall survival (mOS) of untreated and treated patients was evaluated. Analyses were stratified by age (<75 vs ≥75 years

SUBMITTER: van Hoogstraten LMC 

PROVIDER: S-EPMC9790563 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature