Exercise history predicts focal differences in bone volume fraction, mineral density and microdamage in the proximal sesamoid bones of Thoroughbred racehorses.

ABSTRACT: Medial proximal sesamoid bones (PSBs) from Thoroughbred racehorses that did (Case) or did not (Control) experience unilateral biaxial PSB fracture were evaluated for bone volume fraction (BVF), apparent mineral density (AMD), tissue mineral density (TMD), and microdamage in Case fractured, Case contralateral limb intact, and Control bones. A majority of Case bones had a subchondral lesion with high microdamage density, and low BVF, AMD, and TMD. Lesion microdamage and densitometric measures were associated with training history by robust linear regression. Exercise intensity was negatively related to BVF (0.07 ≤ R²  ≤ 0.12) and positively related to microcrack areal density (0.21 ≤ R²  ≤ 0.29) in the lesion; however, in an undamaged site, the relationships were opposi

SUBMITTER: Shaffer SK 

PROVIDER: S-EPMC9790587 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature