Glucose and fatty acids catabolism during in vitro decidualization of human endometrial stromal cells.

ABSTRACT: The differentiation of endometrial stromal cells, named decidualization, is essential for the proper formation of the materno-fetal interphase. One important feature of decidualization is the increased glucose consumption and its utilization by endometrial cells to produce energy. Besides glucose, fatty acids are another important energy source for living cells and it has been described that endometrial stromal cells rely on the proper function of the oxidation of fatty acids for the correct decidualization. It is, however, unknown whether the turn-over of fatty acid degradation is modified during decidualization. Furthermore, it is also unknown how the final products of glucose and fatty acid catabolism are related to the function of the tricarboxylic acid cycle for the efficient ATP prod

SUBMITTER: Citrinovitz ACM 

PROVIDER: S-EPMC9790837 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature