New comprehensive reference values for kidney function indexes across adult and geriatric ages in Chinese popuplation.

ABSTRACT:

Background and aims

China has the largest number of chronic kidney disease (CKD) patients. Current CKD definition has been challenged recently. We aim to reassess kidney function in healthy Chinese population, to provide a more appropriate reference range (RIs) for diagnosis, treatment, monitoring (or screening) of kidney disease and related research.

Materials and methods

A total of 49627 apparently healthy people aged 18-94 years old were enrolled. Age and sex effects were explored for the kidney function indicators and RIs were calculated non-parametrically.

Results

Albumin's limits were lower than the national RIs, with 5.7 g/L lower in upper limit (UL) and 0.4 g/L lower in lower limit (LL) [RIs: 39.6-49.3 vs 40-55]. The LL of estimate glomerular filtration rate (

SUBMITTER: Li H 

PROVIDER: S-EPMC9791318 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature