All-Cause and Infection-Related Mortality in Staphylococcus aureus Bacteremia, a Multicenter Prospective Cohort Study

ABSTRACT: Abstract

Background

Staphylococcus aureus bacteremia (SAB) is a heterogeneous disease with changing epidemiology due to changing demographics and evolving clinical management. SAB is associated with high mortality, but the current fraction of infection-related mortality is less well quantified.

Methods

In a multicenter prospective cohort study of consecutive patients with SAB, we determined clinical features of SAB and determined 90-day mortality and risk factors of all-cause and infection-related mortality. Infection-related mortality was based on an adjudication committee evaluation.

Results

Four hundred ninety patients with SAB were included, with community-acquired (n = 166), health care–associated (n = 163), and hospital-acquired SAB (n = 161). Endocarditis

SUBMITTER:  

PROVIDER: S-EPMC9792080 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature