Alternative sampling specimens for the molecular detection of mpox (formerly monkeypox) virus.

ABSTRACT:

Background

Mpox (formerly monkeypox) is a viral disease caused by the mpox virus (MPXV), endemic in Central and West Africa and currently causing a global outbreak of international concern. Much remains unknown about sample types most suited for mpox laboratory diagnosis. While it is established that high viral loads can be found in active skin lesions (currently the recommended mpox laboratory confirmation specimen type), WHO mpox testing guidelines encourage the use of oropharyngeal swabs as an additional sample type for mpox diagnosis and suggest investigating the value of other specimens like blood samples.

Objective

In this study, we verified the value of select alternative specimen types for mpox laboratory confirmation.

Methods

We included 25 patients with MPXV

SUBMITTER: Coppens J 

PROVIDER: S-EPMC9792191 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature