A circadian rhythm-related biomarker for predicting prognosis and immunotherapy efficacy in lung adenocarcinoma.
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ABSTRACT:
SUBMITTER: Cheng Y
PROVIDER: S-EPMC9792196 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Publications
A circadian rhythm-related biomarker for predicting prognosis and immunotherapy efficacy in lung adenocarcinoma.
Cheng Yuanjun Y Yao Jie J Fang Qianru Q Chen Bin B Zang Guohui G
Aging 20221201 23
Lung adenocarcinoma (LUAD) remains a major reason of cancer-associated mortality globally, and there exists a lack of indicators for survival in LUAD patients. Therefore, it is clinically required to obtain a novel prognostically indicator for guiding clinical management. In this study, we established a circadian rhythm (CR) related signature by a combinative investigation of multiple datasets. The newly-established signature showed an acceptable ability to predict survival and could serve as an ...[more]
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