Tongue and Lip Acceleration as a Measure of Speech Decline in Amyotrophic Lateral Sclerosis.

ABSTRACT:

Purpose

The goal of this study was to examine the efficacy of acceleration-based articulatory measures in characterizing the decline in speech motor control due to amyotrophic lateral sclerosis (ALS).

Method

Electromagnetic articulography was used to record tongue and lip movements during the production of 20 phrases. Data were collected from 50 individuals diagnosed with ALS. Articulatory kinematic variability was measured using the spatiotemporal index of both instantaneous acceleration and speed signals. Linear regression models were used to analyze the relationship between variability measures and intelligible speaking rate (a clinical measure of disease progression). A machine learning algorithm (support vector regression, SVR) was used to assess whether acceleration or

SUBMITTER: Teplansky KJ 

PROVIDER: S-EPMC9792632 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature