AB003. Benefits of proton radiotherapy in thymic epithelial tumors using the model-based approach

ABSTRACT:

Background

Radiotherapy (RT) for thymic epithelial tumors (TET) is indicated postoperatively for advanced/aggressive disease or incomplete resection, or as primary treatment in inoperable patients. In selected patients, proton therapy spares better normal tissues compared to standard photon treatment, and therefore has a high potential to reduce toxicity. The aim of this study is to compare photon and proton plans regarding doses and normal tissue complication probability (NTCP), as a validated surrogate for toxicity.

Methods

Patients with TET referred for radiotherapy from 08.2019–03.2022 were included. Intensity-modulated proton therapy (IMPT) and volumetric-arc photon therapy (VMAT) plans were compared for mean doses to the lungs (MLD), heart (MHD) and esophagus (MED)

SUBMITTER: Peeters S 

PROVIDER: S-EPMC9792829 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature