Associations between plasma metal mixture exposure and risk of hypertension: A cross-sectional study among adults in Shenzhen, China.

ABSTRACT:

Background

Metal exposure affects human health. Current studies mainly focus on the individual health effect of metal exposure on hypertension (HTN), and the results remain controversial. Moreover, the studies assessing overall effect of metal mixtures on hypertension risk are limited.

Methods

A cross-sectional study was conducted by recruiting 1,546 Chinese adults who attended routine medical check-ups at the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen. The plasma levels of 13 metals were measured using inductively coupled plasma mass spectrometry. Multivariate logistic regression model, restricted cubic spline (RCS) model and the Bayesian Kernel Machine Regression (BKMR) model were applied to explore the single and combined effect of metals on the risk o

SUBMITTER: Zheng S 

PROVIDER: S-EPMC9794142 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature