The global burden of cognitive impairment in people with HIV.

ABSTRACT:

Objective

While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for cognitive impairment are used and resource availability differs across geographical settings. We aim to explore this heterogeneity and estimate the global cognitive impairment burden in PWH.

Design

Systematic literature review and meta-analysis.

Methods

We searched PubMed, Embase, SCOPUS, and Web of Science for studies reporting on cognitive impairment prevalence in PWH. Nine factors were investigated for their potential association with the prevalence using a univariate meta-analysis and a meta-regression: assessment method, geograp

SUBMITTER: Keng LD 

PROVIDER: S-EPMC9794154 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature