Enzyme Inhibitory Activities of Extracts and Carpachromene from the Stem of Ficus benghalensis.

ABSTRACT: Ficus benghalensis is one of the potential medicinal plants which is used locally for the treatment of various ailments such as diabetes, antiasthmatic, and wound healing. To provide a scientific background to these folklores, the current study was designed to evaluate the extract and isolated compound against various enzymes such as ureases, tyrosinase, and phosphodiesterase. The methanolic extract and carpachromene demonstrated a significant urease inhibition effect with maximum percent inhibition of 72.09 and 92.87%, respectively. Regarding the tyrosinase inhibition, the percent antagonist effect of carpachromene and the methanolic extract was 84.80 and 70.98%, respectively. The phosphodiesterase was also significantly antagonized by crude extract and carpachromene with a maximum

SUBMITTER: Rauf A 

PROVIDER: S-EPMC9794428 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature