Artificial temperature-compensated biological clock using temperature-sensitive Belousov-Zhabotinsky gels.

ABSTRACT: The circadian rhythm is a fundamental physiological function for a wide range of organisms. The molecular machinery for generating rhythms has been elucidated over the last few decades. Nevertheless, the mechanism for temperature compensation of the oscillation period, which is a prominent property of the circadian rhythm, is still controversial. In this study, we propose a new mechanism through a chemically synthetic approach (i.e., we realized temperature compensation by the Belousov-Zhabotinsky (BZ) gels). The BZ gels are prepared by embedding a metal catalyst of the BZ reaction into the gel polymer. We made the body of BZ gels using a temperature-sensitive polymer gel, which enabled temperature compensation of the oscillation by using temperature dependence of volume. Moreover, we cons

SUBMITTER: Yamada Y 

PROVIDER: S-EPMC9794784 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature