Driver characteristics associated with structurally and electrically remodeled atria in persistent atrial fibrillation.

ABSTRACT:

Background

Recent studies suggest persistent atrial fibrillation (AF) is maintained by localized focal or rotational electrical activations termed drivers.

Objective

The purpose of this study was to evaluate how left atrial (LA) dilation and time in AF impact persistent AF mechanisms.

Methods

Patients with persistent AF <2 years underwent electrocardiographic image mapping. Potential drivers (PDs) were defined as rotational wavefront activity ≥1.5 revolutions or focal activations. Distribution of PDs was recorded using an 18-segment model.

Results

One hundred patients were enrolled (age 61.3 ± 12.1 years). Of these patients, 47 were hypertensive, 14 had diabetes mellitus, and 10 had ischemic heart disease. AF duration was 8 [5-15] months. Median LA diameter was

SUBMITTER: Dhillon GS 

PROVIDER: S-EPMC9795306 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature