Ontology highlight
ABSTRACT:
SUBMITTER: Bernstein MN
PROVIDER: S-EPMC9795364 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Bernstein Matthew N MN Ni Zijian Z Prasad Aman A Brown Jared J Mohanty Chitrasen C Stewart Ron R Newton Michael A MA Kendziorski Christina C
Cell reports methods 20221213 12
Recent advances in spatially resolved transcriptomics technologies enable both the measurement of genome-wide gene expression profiles and their mapping to spatial locations within a tissue. A first step in spatial transcriptomics data analysis is identifying genes with expression that varies spatially, and robust statistical methods exist to address this challenge. While useful, these methods do not detect spatial changes in the coordinated expression within a group of genes. To this end, we pr ...[more]