Neoadjuvant radiotherapy for resectable retroperitoneal sarcoma: a meta-analysis.

ABSTRACT:

Background

Neoadjuvant radiotherapy (NRT) for resectable retroperitoneal sarcoma (RPS) has been shown to be systematically feasible. Whether NRT has equivalent or better clinical effects compared to surgery alone for RPS patients remains controversial.

Methods

We performed a systematic literature search of PubMed, Web of Science, Embase, ASCO Abstracts, and Cochrane library databases for studies in humans with defined search terms. Articles were independently assessed by 2 reviewers, and only randomized controlled trials and cohort studies were included. The hazard ratios (HRs) of overall survival (OS), recurrence-free survival (RFS), and local recurrence (LR) were extracted from included studies. Heterogeneity among study-specific HRs was assessed by the Q statistic and I

SUBMITTER: Li X 

PROVIDER: S-EPMC9795731 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature