Residual cancer is a strong predictor of survival in T3 incidental gallbladder cancer.

ABSTRACT:

Background and purpose

Index cholecystectomy is insufficient for curing T3 incidental gallbladder cancer (IGC), and once residual cancer (RC) is found, the prognosis is often poor. The purpose of this study was to investigate the effect of RC on the prognosis and the optimal choice of adjuvant therapy for R0 reresection patients with T3 IGC.

Methods

We retrospectively reviewed data from patients with T3 IGC who underwent radical reresection from January 2013 to December 2018. RC was defined as histologically proven cancer at reresection. Demographics and tumour treatment-related variables were analysed in correlation with RC and survival. Adjuvant (Adj) chemoradiotherapy (CRT) was correlated with overall survival (OS) and disease-free survival (DFS).

Results

Of the 16

SUBMITTER: You C 

PROVIDER: S-EPMC9795786 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature