Omics technologies in allergy and asthma research: An EAACI position paper.

ABSTRACT: Allergic diseases and asthma are heterogenous chronic inflammatory conditions with several distinct complex endotypes. Both environmental and genetic factors can influence the development and progression of allergy. Complex pathogenetic pathways observed in allergic disorders present a challenge in patient management and successful targeted treatment strategies. The increasing availability of high-throughput omics technologies, such as genomics, epigenomics, transcriptomics, proteomics, and metabolomics allows studying biochemical systems and pathophysiological processes underlying allergic responses. Additionally, omics techniques present clinical applicability by functional identification and validation of biomarkers. Therefore, finding molecules or patterns characteristic for distinct i

SUBMITTER: Radzikowska U 

PROVIDER: S-EPMC9796060 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature