Synthesis of Saturated N‐Heterocycles via a Catalytic Hydrogenation Cascade

ABSTRACT: Abstract Saturated N‐heterocycles are prominent motifs found in various natural products and pharmaceuticals. Despite the increasing interest in this class of compounds, the synthesis of saturated bicyclic azacycles requires tedious multi‐step syntheses. Herein, we present a one‐pot protocol for the synthesis of octahydroindoles, decahydroquinolines, and octahydroindolizines through a cascade reaction.

SUBMITTER: Wagener T 

PROVIDER: S-EPMC9796080 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature