Cow's milk and egg protein threshold dose distributions in children tolerant to beef, baked milk, and baked egg.

ABSTRACT:

Background

The use of eliciting doses (EDs) for food allergens is necessary to inform individual dietary advice and food allergen risk-management. The Eliciting Dose 01 (ED01) for milk and egg, calculated from populations of allergic subjects undergoing oral food challenges (OFCs), are 0.2 mg total protein. The respective Eliciting Dose 05 (ED05) is 2.4 mg for milk and 2.3 mg for egg. As about 70% children allergic to such foods may tolerate them when baked, we sought to verify the EDs of that subpopulation of milk and egg-allergic children.

Methods

We retrospectively assessed consecutive OFC for fresh milk and egg between January 2018 and December 2020 in a population of baked food-tolerant children.

Results

Among 288 children (median age 56 - IQR 36-92.5 months, 67.

SUBMITTER: Valluzzi RL 

PROVIDER: S-EPMC9796240 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature