Structural magnetic resonance imaging in dystonia: A systematic review of methodological approaches and findings.

ABSTRACT:

Background and purpose

Structural magnetic resonance techniques have been widely applied in neurological disorders to better understand tissue changes, probing characteristics such as volume, iron deposition and diffusion. Dystonia is a hyperkinetic movement disorder, resulting in abnormal postures and pain. Its pathophysiology is poorly understood, with normal routine clinical imaging in idiopathic forms. More advanced tools provide an opportunity to identify smaller scale structural changes which may underpin pathophysiology. This review aims to provide an overview of methodological approaches undertaken in structural brain imaging of dystonia cohorts, and to identify commonly identified pathways, networks or regions that are implicated in pathogenesis.

Methods

Structural

SUBMITTER: MacIver CL 

PROVIDER: S-EPMC9796340 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature