A systematic review and meta-analysis of treatments for rapid cycling bipolar disorder.

ABSTRACT:

Objectives

Rapid cycling is a common and disabling phenomenon in individuals with bipolar disorders. In the absence of a recent literature examination, this systematic review and meta-analysis aimed to synthesise the evidence of efficacy, acceptability and tolerability of treatments for individuals with rapid cycling bipolar disorder (RCBD).

Method

A systematic search was conducted to identify randomised controlled trials assigning participants with RCBD to pharmacological and/or non-pharmacological interventions. Study inclusion and data extraction were undertaken by two reviewers independently. The primary outcome was continuous within-subject RCBD illness severity before and after treatment. Pre-post random effects meta-analyses were conducted for each outcome/interventio

SUBMITTER: Strawbridge R 

PROVIDER: S-EPMC9796364 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature