Donor eligibility criteria and liver graft acceptance criteria during normothermic regional perfusion: A systematic review.

ABSTRACT: Acceptance of liver grafts from donations after circulatory death (DCD) largely remains a "black box," particularly due to the unpredictability of the agonal phase. Abdominal normothermic regional perfusion (aNRP) can reverse ischemic injury early during the procurement procedure, and it simultaneously enables graft viability testing to unravel this black box. This review evaluates current protocols for liver viability assessment to decide upon acceptance or decline during aNRP. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was used, and relevant literature databases were searched. The primary outcome consisted of criteria for liver graft viability assessment. Secondary outcomes included survival, primary nonfunction (PNF), early dysfunction, and

SUBMITTER: Schurink IJ 

PROVIDER: S-EPMC9796375 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature