Liver growth prediction in ALPPS - A multicenter analysis from the international ALPPS registry.

ABSTRACT:

Background

While ALPPS triggers a fast liver hypertrophy, it is still unclear which factors matter most to achieve accelerated hypertrophy within a short period of time. The aim of the study was to identify patient-intrinsic factors related to the growth of the future liver remnant (FLR).

Methods

This cohort study is composed of data derived from the International ALPPS Registry from November 2011 and October 2018. We analyse the influence of demographic, tumour type and perioperative data on the growth of the FLR. The volume of the FLR was calculated in millilitre and percentage using computed-tomography (CT) scans before and after stage 1, both according to Vauthey formula.

Results

A total of 734 patients were included from 99 centres. The median sFLR at stage 1 and

SUBMITTER: Lopez-Lopez V 

PROVIDER: S-EPMC9796398 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature