Infection-competent monkeypox virus contamination identified in domestic settings following an imported case of monkeypox into the UK.

ABSTRACT: An imported case of monkeypox was diagnosed in December 2019 in a traveller returning from Nigeria to the UK. Subsequently, environmental sampling was performed at two adjoining single-room residences occupied by the patient and their sibling. Monkeypox virus DNA was identified in multiple locations throughout both properties, and monkeypox virus was isolated from several samples 3 days after the patient was last in these locations. Positive samples were identified following the use of both vacuum and surface sampling techniques; these methodologies allowed for environmental analysis of potentially contaminated porous and non-porous surfaces via real-time quantitative reverse transcriptase PCR analysis in addition to viral isolation to confirm the presence of infection-competent virus. Thi

SUBMITTER: Atkinson B 

PROVIDER: S-EPMC9796424 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature