The risk of renal comorbidities in celiac disease patients depends on the phenotype of celiac disease.

ABSTRACT:

Background

An increased risk of kidney disease in patients with celiac disease has been reported, but the association has remained obscure. Only few studies have investigated the association between renal comorbidities and dermatitis herpetiformis, a cutaneous manifestation of celiac disease.

Objectives

We investigated whether patients with different phenotypes of celiac disease are at higher risk of kidney diseases than age- and sex-matched references.

Methods

The diagnoses of glomerulonephritis, diabetic nephropathy, interstitial nephritis, and end-stage renal disease obtained from the National Hospital Discharge Register between 1970 and 2015 were identified in celiac disease (Marsh III, n = 1072) and dermatitis herpetiformis (n = 368) patients diagnosed at Tampere

SUBMITTER: Nurmi R 

PROVIDER: S-EPMC9796855 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature