Genotypic-specific heat shock response of vector susceptibility to Schistosoma mansoni.

ABSTRACT: Living organisms are vulnerable to thermal stress which causes a diversity of physiological outcomes. Previous work has shown that the snail vectors (Biomphalaria glabrata) of an important human pathogen, Schistosoma mansoni, revert from resistant to susceptible after short exposure to a heat stress as low as 31^oC; however, due to lack of replicability among labs and genetic lines of snails, it has been hypothesized that this effect is genotype dependent. We examined the effects of heat shock on resistance of two species of snail vectors including B. glabrata and B. sudanica. We used 3 different inbred laboratory snail lines in addition to the F1 generation of field collected snails from Lake Victoria, Kenya, an area with high levels of schistosomiasi

SUBMITTER: Spaan JM 

PROVIDER: S-EPMC9797131 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature