Survival After Invasive or Conservative Management of Stable Coronary Disease.

ABSTRACT:

Background

The ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) compared an initial invasive versus an initial conservative management strategy for patients with chronic coronary disease and moderate or severe ischemia, with no major difference in most outcomes during a median of 3.2 years. Extended follow-up for mortality is ongoing.

Methods

ISCHEMIA participants were randomized to an initial invasive strategy added to guideline-directed medical therapy or a conservative strategy. Patients with moderate or severe ischemia, ejection fraction ≥35%, and no recent acute coronary syndromes were included. Those with an unacceptable level of angina were excluded. Extended follow-up for vital status is being conducted by

SUBMITTER: Hochman JS 

PROVIDER: S-EPMC9797439 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature