Comparison of different insulin resistance surrogates to predict hyperuricemia among U.S. non-diabetic adults

ABSTRACT:

Purpose

Although it has been well-acknowledged that insulin resistance (IR) plays a critical role in the development of hyperuricemia (HU), specific relationship between IR and HU in non-diabetic patients remains rarely studied, and there is still no large-scale research regarding this issue. This study aims to explore the association between triglyceride glucose (TyG), TyG with body mass index (TyG-BMI), the ratio of triglycerides divided by high-density lipoprotein cholesterol (TG/HDL-C), metabolic score for insulin resistance (METS-IR), and the risk of HU in non-diabetic patients in The United States of America.

Patients and methods

Data from the National Health and Nutrition Examination Survey (NHANES) enrolling a representative population aged ≥18-year-old were inclu

SUBMITTER: Wang H 

PROVIDER: S-EPMC9797589 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature