Cognitive phenotypes in late-life depression.

ABSTRACT:

Objective

To identify cognitive phenotypes in late-life depression (LLD) and describe relationships with sociodemographic and clinical characteristics.

Design

Observational cohort study.

Setting

Baseline data from participants recruited via clinical referrals and community advertisements who enrolled in two separate studies.

Participants

Non-demented adults with LLD (n = 120; mean age = 66.73 ± 5.35 years) and non-depressed elders (n = 56; mean age = 67.95 ± 6.34 years).

Measurements

All completed a neuropsychological battery, and individual cognitive test scores were standardized across the entire sample without correcting for demographics. Five empirically derived cognitive domain composites were created, and cluster analytic approaches (

SUBMITTER: Szymkowicz SM 

PROVIDER: S-EPMC9797624 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature