In a Real-Life Setting, Direct-Acting Antivirals to People Who Inject Drugs with Chronic Hepatitis C in Turkey.

ABSTRACT:

Background

People who inject drugs (PWID) should be treated in order to eliminate hepatitis C virus in the world. The aim of this study was to compare direct-acting antivirals treatment of hepatitis C virus for PWID and non-PWID in a real-life setting.

Methods

We performed a prospective, non-randomized, observational multicenter cohort study in 37 centers. All patients treated with direct-acting antivirals between April 1, 2017, and February 28, 2019, were included. In total, 2713 patients were included in the study among which 250 were PWID and 2463 were non-PWID. Besides patient characteristics, treatment response, follow-up, and side effects of treatment were also analyzed.

Results

Genotype 1a and 3 were more prevalent in PWID-infected patients (20.4% vs 9.9% and 4

SUBMITTER: Sarıgul Yıldırım F 

PROVIDER: S-EPMC9797763 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature