A personal acquisition time regimen of ⁶⁸Ga-DOTATATE total-body PET/CT in patients with neuroendocrine tumor (NET): a feasibility study.

ABSTRACT:

Background

The injection activity of tracer, acquisition time, patient-specific photon attenuation, and large body mass, can influence on image quality. Fixed acquisition time and body mass related injection activity in clinical practice results in a large difference in image quality. Thus, this study proposes a patient-specific acquisition time regimen of ⁶⁸ Ga-DOTATATE total-body positron emission tomography-computed tomography (PET/CT) to counteract the influence of body mass (BM, kg) on image quality, and acquire an acceptable and constant image of patients with neuroendocrine tumors (NETs).

Methods

The development cohort consisting of 19 consecutive patients with full activity (88.7-204.9 MBq, 2.0 ± 0.1 MBq/kg) was to establish the acquisition time regimen. T

SUBMITTER: Xiao J 

PROVIDER: S-EPMC9798642 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature