Effect of intravenous antihypertensives on outcomes of severe hypertension in hospitalized patients without acute target organ damage.

ABSTRACT:

Background

Treatment of severe inpatient hypertension (HTN) that develops during hospitalization is not informed by guidelines. Intravenous (i.v.) antihypertensives are used to manage severe HTN even in the absence of acute target organ damage; however they may result in unpredictable blood pressure (BP) reduction and cardiovascular events. Our goal was to assess the association between i.v. antihypertensives and clinical outcomes in this population.

Methods

This is a multihospital retrospective study of adults admitted for reasons other than HTN who develop severe HTN during hospitalization without acute target end organ damage. We defined severe HTN as BP elevation of systolic >180 or diastolic >110 mmHg. Treatment was defined as receiving i.v. antihypertensives within 3 h

SUBMITTER: Ghazi L 

PROVIDER: S-EPMC9799038 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature