Intraoperative electrical stimulation of the human dorsal spinal cord reveals a map of arm and hand muscle responses.

ABSTRACT: Although epidural stimulation of the lumbar spinal cord has emerged as a powerful modality for recovery of movement, how it should be targeted to the cervical spinal cord to activate arm and hand muscles is not well understood, particularly in humans. We sought to map muscle responses to posterior epidural cervical spinal cord stimulation in humans. We hypothesized that lateral stimulation over the dorsal root entry zone would be most effective and responses would be strongest in the muscles innervated by the stimulated segment. Twenty-six people undergoing clinically indicated cervical spine surgery consented to mapping of motor responses. During surgery, stimulation was performed in midline and lateral positions at multiple exposed segments; six arm and three leg muscles were recorded on

SUBMITTER: McIntosh JR 

PROVIDER: S-EPMC9799146 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature