Accuracy of serological tests for COVID-19: A systematic review and meta-analysis.

ABSTRACT:

Objective

To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (COVID-19).

Methods

PubMed, Embase and the Cochrane Library were searched from January 1 2020 to September 2 2022. We included studies that measured the sensitivity, specificity or both qualities of a COVID-19 serological test and a reference standard of a viral culture or reverse transcriptase polymerase chain reaction (RT-PCR). The risk of bias was assessed by using quality assessment of diagnostic accuracy studies 2 (QUADAS-2). The primary outcomes included overall sensitivity and specificity, as stratified by the methods of serological testing [enzyme-linked immunosorbent assays (ELISAs), lateral flow immunoassays (LFIAs) or chemiluminescent immunoassays (CLIAs)] and immunogl

SUBMITTER: Zheng X 

PROVIDER: S-EPMC9800917 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature