Intraoperative challenges after induction therapy for non–small cell lung cancer: Effect of nodal disease on technical complexity

ABSTRACT:

Objectives

Neoadjuvant therapy has been theorized to increase complexity of non–small cell lung cancer resections; however, specific factors that contribute to intraoperative challenges after induction therapy have not been well described. We aimed to characterize the effect of nodal involvement and nodal treatment response on surgical complexity after neoadjuvant therapy.

Methods

We identified patients treated with neoadjuvant therapy followed by anatomic lung resection for cN + non–small cell lung cancer between 2010 and 2020. Patients were categorized according to clinical N1 versus N2 disease. To evaluate the effect of nodal response to therapy, thoracic radiologists measured clinically suspected and pathologically involved lymph nodes before and after induction thera

SUBMITTER: Feldman H 

PROVIDER: S-EPMC9801337 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature